李莎,毕业于山东大学微生物系,在美国芝加哥大学获得博士学位。曾在美国西北大学任Research Associate,康奈尔大学任Research Associate 和Visiting Scientist。yl23455永利官方2019年海外高层次引进人才。
研究方向
免疫学:从细胞和分子角度研究宿主对入侵病原微生物的免疫应答。
药理学生物信息分析:融合药理学、生物信息学、计算机科学等多学科的技术和内容,阐述中草药在疾病中潜在的作用机制。
代表性论文(*通讯作者)
[1] Mingzhi Li, Shiqi Weng, Quansheng Wang, Zibing Yang, Xiaoling Wang, Yanjun Yin, Qiuxiang Zhou, Lirong Zhang, Feifei Tao, Yihan Li, Mengle Jia, Lingdi Yang, Xiu Xin, Hanguang Li, Lumei Kang, Yu Wang1*, Ting Wang1*, Sha Li1*, Lingbao Kong1*. Reduced binding activity of vaccine serum to omicron receptor-binding domain. Front. Immunol., 28 July 2022.
[2] Jiawu Wan, Ting Wang, Jing Xu, Tao Ouyang, Qianruo Wang, Yanni Zhang, Shiqi Weng, Yihan Li, Yu Wang1, Xiu Xin, Xiaoling Wang, Sha Li*, Lingbao Kong*. Novel Japanese encephalitis virus NS1-based vaccine: truncated NS1 fused with E.coli heat-labile enterotoxin B subunit. EBioMedicine. 2021; 67(17):103353.
[3] Zibing Yang, Tao Ouyang , Haruyo Aoyagi , Ting Wang, Xiu Xing, Yanni Zhang, Yu Wang, Yihan Li, Hideki Aizaki* , Sha Li *, Lingbao Kong*. Cellular OCIAD2 protein is a proviral factor for hepatitis C virus replication. Int J Biol Macromol. 2021; 188:147-159.
[4] Bagchi, S.1†, S. Li1†, and C. Wang. CD1b-autoreactive T cells recognize phospholipid antigens and contribute to antitumor immunity against a CD1b+ T cell lymphoma. OncoImmunology. 2016. 5(9): p. e1213932. (并列一作)
[5]Laura A. Sena, Sha Li, Amit Jairaman, Murali Prakriya, Teresa Ezponda, David A. Hildeman, Chyung-Ru Wang, Paul T. Schumacker, Jonathan D. Licht, Harris Perlman, Paul J. Bryce, Navdeep S. Chandel.Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling. Immunity February 15, 2013.
[6] Sha Li, Hak-Jong Choi, Kyrie Felio, Chyung-Ru Wang. Autoreactive CD1b-restricted T cells: a new innate-like T-cell population that contributes to immunity against infection. Blood 2011; 118 (14): 3870–3878.